Education:

BS (1985),  Xiamen University

MS (1988),  Xiamen University

PhD (1991),  Xiamen University

Selected Recent Publications:

1. Chen, L. D.; Zhang, D.; Li, Z. H.; Li, Z.; Cai, S. L.*; Cao, S. H.*; Li, Y. Q.*, Designing Fluorescent Interfaces at Hotspots in a Plasmonic Nanopore for Homologous Optoelectronic Sensing. Small 2025, 21, 2410237.

2. Wei, J. W.; He, J. R.; Chen, S. Y.; Guo, Y. H.; Huo, X. Z.; Zheng, N.; Cao, S. H.; Li, Y. Q.*, Synchronous fluorescence spectra-based machine learning algorithm with quick and easy accessibility for simultaneous quantification of polycyclic aromatic hydrocarbons in edible oils. Food Control 2024, 158, 9.

3. Wang, J. D.; Zhao, Y.; Ghorai, S. K.; Li, Z.; Weng, Y. H.; Cao, S. H.*; Li, Y. Q.*, Derivative-synchronous fluorescence spectroscopy enhanced surface plasmon coupled emission for sensitive detection of tannic acid. Sensor Actuat. B-Chem 2024, 413, 7.

4. Lv, H. Z.; Chen, J. L.; Zhao, Y.; Li, Y.; Cao, S. H.; Cai, W. P.; Shen, L.*; Lu, Y. H.; Li, Y. Q.*, A novel derivative synchronous fluorescence method for the rapid, non-destructive and intuitive differentiation of denitrifying bacteria. J Environ Manage 2024, 356, 9.

5. Xu, L. T.; Xie, K. X.; Cao, S. H.; Weng, Y. H.; Chen, M.; Li, Z.; Li, Y. Q.*, Simultaneous monitoring of the fluorescence and refractive index by surface plasmon coupled emission: A proof-of-concept study. Chin Chem Lett 2023, 34 (10), 4.

6. Zhao, Y.; Cao, S. H.*; Wang, J. D.; Li, N.; Lin, G. C.; Li, Y. Q.*, Polarization- and Angle-Dependent Plasmonic Synchronous Fluorescence Spectroscopy to Probe Molecular Vibrational Couplings on an Aluminum Nano-Film. Adv Opt Mater 2022, 10 (8), 9.

7. Xu, L. T.; Chen, M.; Weng, Y. H.; Xie, K. X.; Wang, J.; Cao, S. H.*; Li, Y. Q.*, Label-Free Fluorescent Nanofilm Sensor Based on Surface Plasmon Coupled Emission: In Situ Monitoring the Growth of Metal-Organic Frameworks. Anal Chem 2022, 94 (17), 6430-6435.

8. He, J. R.; Wei, J. W.; Chen, S. Y.; Li, N.; Zhong, X. D.; Li, Y. Q.*, Machine Learning-Assisted Synchronous Fluorescence Sensing Approach for Rapid and Simultaneous Quantification of Thiabendazole and Fuberidazole in Red Wine. Sensors 2022, 22 (24), 13

9. Wu, Y. Y.; Chen, L. D.; Cai, X. H.; Zhao, Y.; Chen, M.; Pan, X. H.; Li, Y. Q.*, Smart pH-Modulated Two-Way Photoswitch Based on a Polymer-Modified Single Nanochannel. ACS Appl Mater Interfaces 2021, 13 (21), 25241-25249

10. Pan, X. H.; Chen, M.; Cao, S. H.; Xu, Z. Q.; Li, Z.; Li, Y. Q.*, Plasmon Coupling Enhanced Micro-Spectroscopy and Imaging for Sensitive Discrimination of Membrane Domains of a Single Cell. Chem Euro J 2021, 27 (69), 17331-17335.

11. Zhao, Y.; Liu, Y. H.; Cao, S. H.*; Ajmal, M.; Zhai, Y. Y.; Pan, X. H.; Chen, M.; Li, Y. Q.*, Excitation-Emission Synchronization-Mediated Directional Fluorescence: Insight into Plasmon-Coupled Emission at Vibrational Resolution. J Phys Chem Lett 2020, 11 (7), 2701-2707.

12. Chen, M.; Pan, X. H.; Liu,  Q.; Huo, S. X.; Cao, S. H.; Zhai, Y. Y.; Zhao, Y.; Li, Y. Q.*, Variable-Angle Nanoplasmonic Fluorescence  Microscopy: An Axially Resolved Method for Tracking the Endocytic Pathway.  Anal Chem 2019, 91 (21),      13658-13664.

13. Xie, K. X.; Xu, L. T.; Zhai, Y. Y.; Wang, Z. C.; Chen, M.; Pan, X. H.; Cao, S. H*.; Li, Y. Q.*, The synergistic  enhancement of silver nanocubes and graphene oxide on surface  plasmon-coupled emission. Talanta 2019, 195, 752-756.

14. Weng, Y. H.; Xu, L. T.; Chen, M.; Zhai, Y. Y.;  Zhao, Y.; Ghorai, S. K.; Pan, X. H.; Cao, S. H.*; Li, Y. Q.*, In Situ Monitoring of Fluorescent Polymer Brushes  by Angle-Scanning Based Surface Plasmon Coupled Emission. ACS Macro Lett 2019, 8 (2),      223-227.

15. Zheng, Y. B.; Zhao, S.; Cao, S. H.; Cai, S.  L.; Cai, X. H.; Li, Y. Q.*, A  temperature, pH and sugar triple-stimuli-responsive nanofluidic diode. Nanoscale 2017, 9 (1), 433-439

16. Cai, W. P.; Zhai, Y. Y.; Cao, S. H.; Liu, Q.;  Weng, Y. H.; Xie, K. X.; Lin, G. C.; Li, Y. Q.*，High performance dual-mode surface plasmon  coupled emission imaging apparatus integrating Kretschmann and reverse   Kretschmann configurations for flexible measurements. Rev Sci  Instrum 2016, 87, 5.

17. Cai, S. L.; Zheng, Y. B.; Cao, S. H.; Cai, X.  H.; Li, Y. Q.*, A conformation and charge co-modulated ultrasensitive      biomimetic ion channel. Chem Commun 2016,52, 12450-12453

18. Liu, Y. H.; Wu, P. P.; Liu, Q.; Luo, H. D.;  Cao, S. H.; Lin, G. C.; Fu, D. S.; Zhong, X. D.; Li, Y. Q.*,A  Simple Fluorescence Spectroscopic Approach for Simultaneous and Rapid  Detection of Four Polycyclic Aromatic Hydrocarbons (PAH4) in Vegetable      Oils. Food Anal Method 2016, 9, 3209-3217.

19. Cai, S. L.; Cao, S. H.; Zheng, Y. B.; Zhao,  S.; Yang, J. L.; Li, Y. Q.*, Surface charge modulated  aptasensor in a single glass conical nanopore. Biosens Bioelectron 2015, 71, 37-43.

20. Xie, K. X.; Cao, S. H.; Liu, Q.; Cai, W. P.;  Huo, S. X.; Watarai, H.; Li, Y. Q.*, Modulation of surface  plasmon coupled emission (SPCE) by a pulsed magnetic field. Chem Commun 2015, 51, 12320-12323.

21. Liu, Q.; Cao, S. H.; Cai, W. P.; Liu, X. Q.;  Weng, Y. H.; Xie, K. X.; Huo, S. X.; Li, Y. Q.*, Surface  Plasmon Coupled Emission in Micrometer-Scale Cells: A Leap from Interface  to Bulk Targets. J Phys Chem B 2015, 119,  2921-2927.

22. Huo, S. X.; Liu, Q.; Cao, S. H.; Cai, W. P.;  Meng, L. Y.; Xie, K. X.; Zhai, Y. Y.; Zong, C.; Yang, Z. L.; Ren, B.; Li,  Y. Q.*, Surface Plasmon-Coupled Directional Enhanced Raman Scattering      by Means of the Reverse Kretschrnann Configuration. J Phys Chem  Lett 2015, 6, 2015-2019.

23. Cao, S. H.; Zou, Z. X.; Weng, Y. H.; Cai, W.  P.; Liu, Q.; Li, Y. Q.*, Plasmon-mediated fluorescence with  distance independence: From model to a biosensing application. Biosens  Bioelectron 2014, 58, 258-265.

24. Cao, S. H.; Cai, W. P.; Liu, Q.; Xie, K. X.;      Weng, Y. H.; Huo, S. X.; Tian, Z. Q.; Li, Y. Q.*, Label-Free  Aptasensor Based on Ultrathin-Linker-Mediated Hot-Spot Assembly To Induce      Strong Directional Fluorescence. J Am Chem Soc 2014,      136, 6802-6805.

25. Zhao, S.; Zheng, Y. B.; Cai, S. L.; Weng, Y.      H.; Cao, S. H.; Yang, J. L.; Li, Y. Q.*, Sugar-stimulated      robust nanodevice: 4-Carboxyphenylboronic acid modified single glass      conical nanopores. Electrochem Commun 2013, 36,      71-74.

26. Liu, Q.; Huang, W.; Shindi, A. A. F.; Li, Y. Q.*, A novel rapid method for simultaneous determination of three      diagnostically important porphyrins in erythrocytes using hyphenated synchronous fluorescence techniques. Talanta 2012,  88, 663-668.

27. Li, Y. Q.*; Zheng, Y. B.; Zare, R. N.*, Electrical, Optical, and Docking Properties of Conical Nanopores. ACS Nano 2012, 6,      993-997.

28. Cao, S. H.; Cai, W. P.; Liu, Q.; Li,  Y. Q.*, Surface Plasmon-Coupled Emission: What Can Directional Fluorescence Bring to the Analytical Sciences? Annu Rev Anal Chem 2012, 5, 317-336.

29. Zhang, L. X.; Cai, S. L.; Zheng, Y. B.; Cao,  X. H.; Li, Y. Q.*, Smart Homopolymer Modification to Single Glass Conical Nanopore Channels: Dual-Stimuli-Actuated Highly Efficient Ion Gating. Adv Funct Mater 2011, 21, 2103-2107.

30. Li, N.; Li, X. Y.; Zou, Z. X.; Lin, L.R.; Li, Y. Q.* A novel baseline-correction method for standard addition based derivative spectra and its application to quantitative analysis of benzo(a)pyrene in vegetable oil samples. Analyst 2011, 36, 2802-2810.

31. Cao, S. H.; Xie, T. T.; Cai, W. P.; Liu, Q. A.; Li, Y. Q.* Electric Field Assisted Surface Plasmon-Coupled Directional Emission: An Active Strategy on Enhancing Sensitivity for DNA   Sensing and Efficient Discrimination of Single Base Mutation. J Am  Chem Soc 2011, 133, 1787-1789.